? Dynamic and Accurate: CHI3L1 is the driving force of liver fibrogenesis, and dynamic assessment of progression/regression rate of liver fibrosis is better than the traditional static staging of fibrosis (stages 1-4).
? Specific and Sensitive: CHI3L1 has high liver specificity. At the cut-off value of 79ng/ml, the specificity and sensitivity of CHI3L1 for moderate and severe liver fibrosis are both over 90%, higher than other diagnostic methods.
? Non-invasive and Convenient: CHI3L1 is a stable serum biomarker whose level is not affected by ALT levels, ascites, serum bilirubin levels and other common factors. The diagnosis is non-invasive and is based on a single value from a single marker, which offers a safe and convenient method for fibrosis assessment.
A novel diagnostic marker with increased sensitivity for advanced liver fibrosis. Good discrimination for different stages of liver fibrosis using CHI3L1.
? Supported by publications from top universities (e.g. Harvard University) in high-ranking journals
? Used by Lab Corp.-one of the largest diagnostic laboratory service provider in the United States
? CE mark approval
A novel diagnostic marker with increased sensitivity for advanced liver fibrosis (cirrhosis)
?Serum CHI3L1 levels were increased in alcoholic cirrhosis, post-hepatitic cirrhosis and non-cirrhotic fibrosis [6].
?Several studies have established that CHI3L1 is a biomarker for HCV-induced liver fibrosis and cirrhosis [6-9].
?CH13L1 was shown to be a biomarker for HBV-related liver fibrosis and cirrhosis [5].
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